Do Redheads Carry Melanoma Risk Independent of Sun Exposure?

Interesting.  I have had my DNA done by several services primarily for genealogy purposes and on one it points out this connection.  My primary melanoma was on my upper left inner thigh.  I don’t think that I had a lot of sunburns on that particular spot.  While sun exposure certainly makes things worse, it is NOT the sole component in Melanoma and how severe it becomes.

understandcancerin60minutes

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Why are redheads more susceptible to the potentially deadly skin cancer, melanoma?

If you have red hair and fair skin, you are significantly more likely to develop melanoma than are people with darker skin. Sun exposure and ultraviolet (UV) radiation are proven risks for virtually all skin cancers. Among the most potentially deadly skin cancers, melanoma can grow aggressively and can spread if not detected early. Unfortunately, the number of cases is rising at a rate of 3 percent per year, especially among fair-skinned people. Unlike other forms of skin cancer, the increased risk in fair-skinned individuals is not limited to sun-exposed skin, raising the possibility that UV radiation may not be the only risk factor for melanoma.

Research: Investigators at Massachusetts General Hospital (Harvard; USA) worked with a mouse model of the redhead phenotype. The discovered that at least part of the increased risk is unrelated to UV exposure…

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About mcreyscope

Retired / disabled survivor of Stage IV melanoma and paraneoplastic syndrome.
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